KROK 1 2011 – Question 74 · KROK (Medicine) · Pathophysiology

A patient with coronary disease has been diagnosed with myocardial hypertrophy, tachycardia and a decrease in minute blood volume. What is the leading mechanism of cardiac hystiocyte damage in this case?

  1. A. Damage of specific membrane pumps
  2. B. Increase in α and β adrenoreceptors quantity
  3. C. Mg2+ loss by cardiac hystiocytes
  4. D. Cardiac hystiocyte dehydration
  5. E. Ca2+ loss by cardiac hystiocytes
Hint

Coronary disease starves the myocardium of oxygen and energy; think about which energy-dependent transport systems at the myocyte surface fail first, and how ion gradients and calcium and water movement then change.

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