KROK 1 2011 – Question 52 · KROK (Medicine) · Pathophysiology

After transfusion of 200 ml of blood a patient presented with body temperature rise up to 37.9 °C. Which of the following substances is the most likely cause of temperature rise?

  1. A. Interleukin-1
  2. B. Interleukin-3
  3. C. Interleukin-2
  4. D. Tumour necrosis factor
  5. E. Interleukin-4
Hint

Think about which cytokine released by activated monocytes and macrophages acts on the hypothalamic thermoregulatory centre to raise the temperature set point.

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