Question 2 · LEK · Carney complex

Which of the following concerning Carney syndrome is false?

  1. A. is an autosomal dominantly inherited syndrome.
  2. B. is caused by an inactivating mutation of the PRKR1A gene.
  3. C. occurs after puberty, most often in men.
  4. D. Cushing’s syndrome in patients with Carney syndrome can be subclinical, cyclical and overt.
  5. E. increase in cortisol concentration is observed after dexamethasone administration.
Hint

Recall the inheritance, the gene, the typical age and sex of PPNAD-related Cushing syndrome, and the paradoxical dexamethasone response.

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