Question 110 (part 2) · LEK · Ovarian cancer

Tumour markers are substances whose concentration assessment might be used to evaluate the treatment of cancers. Which of the following is false:

  1. A. hCG levels are increased in choriocarcinoma preceded by hydatidiform mole.
  2. B. a high CA-125 level rules out ovarian cancer.
  3. C. inhibin concentration measurement might be useful in granulosa cell tumour treatment monitoring.
  4. D. HE-4 concentration measurement is not used to differentiate uterine sarcomas from myomas .
  5. E. granulosa cell tumours might produce oestrogens.
Hint

Think about how often CA-125 is normal in early-stage or non-serous ovarian cancer and whether any single value can exclude the disease.

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