Question 359 · LEK · Megaloblastic anemia

How should vitamin B₁₂ be supplemented in patients with pernicious anaemia (Addison- Biermer anaemia)?

  1. A. orally on an empty stomach for the rest of their life.
  2. B. orally after a meal for the rest of their life.
  3. C. intramuscular or deep subcutaneous injection for the rest of their life.
  4. D. intramuscular or deep subcutaneous injection for 3 months.
  5. E. vitamin B₁₂ should not be supplemented.
Hint

Consider why B12 is not absorbed in pernicious anemia and whether this defect ever resolves.

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