Question 365 · LEK · Dermatomyositis and polymyositis
Antinuclear antibodies (ANA), specifically reactive with Jo-1 antigen can be found mainly in patients with:
- A. polymyositis.
- B. systemic lupus erythematosus.
- C. rheumatoid arthritis.
- D. seronegative spondyloarthropathy.
- E. degenerative arthritis.
Hint
Jo-1 is an aminoacyl-tRNA synthetase; link it to the syndrome of myositis, interstitial lung disease and mechanic's hands.
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