Question 357 · LEK · Pheochromocytoma and paraganglioma
Pheochromocytoma can have a genetic background. Which of the following clinical data suggest germinal mutation in the patient with pheochromocytoma?
1) tumor diagnosed at the age of 17;
2) bilateral tumors;
3) coexisting hyperparathyroidism;
4) patient with the history of papillary thyroid cancer;
5) paroxysmal hypertension.
The correct answer is:
2) bilateral tumors;
3) coexisting hyperparathyroidism;
4) patient with the history of papillary thyroid cancer;
5) paroxysmal hypertension.
The correct answer is:
- A. all the above.
- B. 1,2.
- C. 1,2,3.
- D. 4,5.
- E. 1,3.
Hint
Germline mutations suggest early onset, multifocal disease and components of hereditary syndromes such as MEN2.
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