Question 304 · LEK · Microscopic colitis
A 64-year-old woman with psoriasis complains of abdominal cramps, watery diarrhoea and weight loss in the last three months since the symptoms first occurred (about 6 kg). She has not been diagnosed with any chronic diseases before. On physical examination increased intestinal peristalsis was noted. In routine laboratory tests no abnormalities were found. Colonoscopy - macroscopically the colon and terminal ileum looked normal. In biopsies obtained from the right half of the colon mild infiltration of lymphocytes and plasmocytes in the lamina propria was found. The most probable diagnosis is:
- A. chronic pancreatitis.
- B. coeliac disease.
- C. irritable bowel syndrome (IBS).
- D. microscopic colitis.
- E. Campylobacter jejuni infection.
Hint
Chronic watery diarrhea with a normal-looking colon in an older woman: what can only the biopsies reveal?
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