Question 303 · LEK · Chronic kidney disease
Which of the following disturbances of calcium and phosphate homeostasis occur in chronic kidney disease?
1) elevated serum PTH concentration;
2) decreased serum FGF-23 (phosphatonin) concentration;
3) decreased calcium concentration;
4) increased phosphate concentration;
5) increased concentration of 1,25(OH)₂D₃.
The correct answer is:
2) decreased serum FGF-23 (phosphatonin) concentration;
3) decreased calcium concentration;
4) increased phosphate concentration;
5) increased concentration of 1,25(OH)₂D₃.
The correct answer is:
- A. 1,3,4.
- B. 2,3,4.
- C. 2,3,5.
- D. 1,3,5.
- E. 3,4,5.
Hint
Start from the failing kidney, which cannot excrete phosphate or activate vitamin D, and follow the hormonal responses.
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