Question 31 · LEK · Treatment

In a patient with long-lasting type 2 diabetes and diabetic kidney disease, until now treated with oral hypoglycemic drugs, further progression of chronic kidney disease has been noted with decrease of glomerular filtration rate down to 15/ml/min/1.73 m². Which of the following drugs can be still used as hypoglycemic agents in this patient?

  1. A. metformin and liraglutide.
  2. B. dapagliflozin and insulin.
  3. C. empagliflozin and glipizide.
  4. D. linagliptin and insulin.
  5. E. sitagliptin and insulin.
Hint

Look for the incretin-based oral agent eliminated mainly via bile, combined with the therapy usable at any level of kidney function.

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