Question 53 (part 2) · LEK · Characteristics of scientific studies

In 2010, researchers began a study on the relationship between the level of cholesterol and stroke. A group of 5,000 healthy people who participated in the cholesterol screening program in 1995 were qualified for the study. The researchers determined exposure categories based on cholesterol levels at the time of screening. The cut-off value of 200 mg/dl was used to define "high" cholesterol, while people with levels below 200 mg/dl were defined as having "low" cholesterol. According to this definition, 2,000 people had "high" cholesterol and the remaining 3,000 people had "low" cholesterol. The researchers found that 300 cases of stroke occurred before the end of 2012, of which 120 occurred in the high cholesterol group. What type of coefficient should the researchers calculate to estimate the strength of the relationship between ”high” cholesterol and stroke risk?

  1. A. odds ratio.
  2. B. prevalence rate.
  3. C. incidence rate.
  4. D. positive predictive value.
  5. E. relative risk.
Hint

Identify the design: groups were defined by exposure and checked for new cases, so incidence in both groups can be compared.

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