Question 34 (part 2) · LEK · Environmental epidemiology

The biomarkers of exposure to tobacco smoke include:

1) concentration of cotinine in urine, blood, saliva.
2) levels of high-molecular-weight DNA adducts in peripheral blood leukocytes.
3) concentration of phthalates in urine.
4) concentration of carboxyhemoglobin in blood.
5) concentration of fluorides in urine.
The correct answer is:
  1. A. all of the above.
  2. B. 1,2,3,4.
  3. C. 1,2,4.
  4. D. 3,4 .
  5. E. only 1.
Hint

Look for markers of nicotine metabolism, carbon monoxide and carcinogen binding to DNA; drop those linked to plastics or toothpaste.

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