Question 40 (part 2) · LEK · Basics of medical statistics

In 2017, the results of a large prospective cohort study were published in the New England Journal of Medicine (NEXT 2017, 377, 2228-39), whose purpose was to analyze the relationship between the use of hormonal contraception and the risk of breast cancer in women. Compared to women who have never used hormonal contraception, the relative risk of breast cancer in women who are currently or have recently used hormonal contraception is 1.20 (95% confidence interval: 1.14 – 1.26). The result obtained indicates that hormonal contraception:

  1. A. statistically insignificantly increases the risk of breast cancer by 20%.
  2. B. statistically significantly increases the risk of breast cancer by 20%.
  3. C. statistically significantly decreases the risk of breast cancer by 20%.
  4. D. statistically significantly increases the risk of breast cancer by 120%.
  5. E. does not significantly affect the risk of breast cancer.
Hint

Check whether the 95% confidence interval includes 1, then translate an RR of 1.20 into a percentage change.

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