Question 39 (part 2) · LEK · Characteristics of scientific studies

The authors of the paper published in the Arquivos de Gastroenterologia journal (2021, vol. 58, pp. 114-9) assessed the evidence for a causal relationship between Helicobacter pylori infection and colorectal cancer. It has been observed that Helicobacter pylori infection in most patients is acquired in their childchood, before the age of 10. Which of Hill's criteria for causation is met by the evidence provided?

  1. A. temporality.
  2. B. consistency.
  3. C. strength.
  4. D. biological gradient.
  5. E. plausibility.
Hint

Acquiring the infection in childhood, decades before cancer develops, says something about the order of events.

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