Question 363 · LEK · Primary autoinflammatory diseases
Indicate false statement regarding the congenital autoinflammatory syndrome PFAPA in children:
- A. the symptoms of PFAPA include: fever, aphthae, pharyngitis, lymphadenitis, and abdominal pain.
- B. the gene responsible for the occurrence of PFAPA is ABC1.
- C. the onset of PFAPA symptoms typically occurs before the age of 5.
- D. the occurrence of PFAPA is not limited to a specific continent - it is a worldwide condition.
- E. the prognosis is good.
Hint
Consider what is known about the genetics, age of onset, distribution and course of PFAPA compared with monogenic periodic fevers.
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