Question 280 · LEK · Hereditary spherocytosis
Jaundice, low hemoglobin levels, high reticulocyte count, elevated indirect bilirubin levels, negative direct antiglobulin test, decreased erythrocyte osmotic resistance and abnormal EMA test result point to:
- A. autoimmune hemolytic anemia.
- B. Fanconi anemia.
- C. Blackfan Diamond anemia.
- D. myelodysplastic syndrome.
- E. spherocytosis.
Hint
A negative Coombs test excludes immune hemolysis; which disorder is detected by reduced eosin-5-maleimide binding to band 3?
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