KROK 1 2010 – Question 127 · KROK (Medicine) · Microbiology, Virology, and Immunology

Examination of a child who frequently suffers from infectious diseases revealed that IgG concentration in blood serum was 10 times less than normal, IgA and IgM concentration was also significantly reduced. Analysis showed also lack of B-lymphocytes and plasmocytes. What disease are these symptoms typical for?

  1. A. Swiss-type agammaglobulinemia
  2. B. Di George syndrome
  3. C. Bruton’s disease
  4. D. Dysimmunoglobulinemia
  5. E. Louis-Bar syndrome
Hint

Combine the reduced immunoglobulin classes with the absence of B cells and plasma cells, and ask whether the defect lies in humoral immunity alone or also in T cells.

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