KROK 1 2010 – Question 26 · KROK (Medicine) · Biological Chemistry

A 62 year woman complains of frequent pain attacks in the area of her chest and backbone, rib fractures. Her doctor suspected myeloma (plasmocytoma). What of the following laboratory characteristics will be of the greatest diagnostic importance?

  1. A. Hyperalbuminemia
  2. B. Hypoglobulinemia
  3. C. Hypoproteinemia
  4. D. Proteinuria
  5. E. Paraproteinemia
Hint

Think about what a single malignant plasma-cell clone secretes into the blood and how that would look on serum protein electrophoresis.

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