KROK 1 2009 – Question 115 · KROK (Medicine) · Biological Chemistry
Vitamin B1 deficiency causes disturbance of oxidative decarboxylation of α-ketoglutaric acid. This leads to the impaired synthesis of the following coenzyme:
- A. Flavine adenine dinucleotide
- B. Lipoic acid
- C. Nicotinamide adenine dinucleotide
- D. Thiamine pyrophosphate
- E. Coenzyme A
Hint
Think of the cofactors of the α-ketoglutarate dehydrogenase complex and which of them is made from the vitamin mentioned in the stem.
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