KROK 1 2009 – Question 92 · KROK (Medicine) · Pathophysiology
As a result of increased permeability of the erythrocyte membrane in a patient with microspherocytic anaemia (Minkowsky-Shauffard disease) cells receive sodium ions and water. Erythrocytes take form of spherocytes and can be easily broken down. What is the leading mechanism of erythrocyte damage in this case?
- A. Nucleic
- B. Calcium
- C. Protein
- D. Electrolytic osmotic
- E. Acidotic
Hint
Consider what the entry of sodium and water through a leaky membrane does to a red cell's volume and shape, and what kind of imbalance that represents.
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