KROK 1 2009 – Question 81 · KROK (Medicine) · Pathophysiology

After transfusion of 200 ml of blood a patient presented with body temperature rise up to 37.9 °C. Which of the following substances is the most likely cause of temperature rise?

  1. A. Interleukin-4
  2. B. Interleukin-1
  3. C. Tumour necrosis factor
  4. D. Interleukin-3
  5. E. Interleukin-2
Hint

Ask which signalling molecule released by activated monocytes and macrophages reaches the hypothalamus and raises the thermoregulatory set-point.

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