KROK 1 2007 – Question 119 · KROK (Medicine) · Microbiology, Virology, and Immunology

48 hours after performing tuberculin test (Mantoux test) to a child a 10 mm papule appeared on the spot of tuberculin introduction. What hypersensitivity mechanism underlies these changes?

  1. A. Cellular cytotoxicity
  2. B. Antibody-dependent cytotoxicity
  3. C. Granulomatosis
  4. D. Immune complex cytotoxicity
  5. E. Anaphylaxis
Hint

Remember that a skin reaction appearing after one to three days rather than within minutes is mediated by sensitised T lymphocytes and macrophages, not by antibodies.

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