KROK 1 2007 – Question 84 · KROK (Medicine) · Pathophysiology
A patient is followed up in an endocrinological dispensary on account of hyperthyreosis. Weight loss, tachycardia, finger tremor are accompanied by hypoxia symptoms - headache, fatigue, eye flicker. What mechanism of thyroid hormones action underlies the development of hypoxia?
- A. Specific binding of active centres of respiratory ferments
- B. Intensification of respiratory ferment synthesis
- C. Disjunction, oxydation and phosphorilation
- D. Inhibition of respiratory ferment synthesis
- E. Competitive inhibition of respiratory ferments
Hint
Think about what excess thyroid hormone does to the coupling between substrate oxidation in mitochondria and ATP formation, so that oxygen is used but energy is lacking.
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