KROK 1 2007 – Question 53 · KROK (Medicine) · Pathophysiology
A patient who suffers from pneumonia has high body temperature. What biologically active substance plays the leading part in origin of this phenomenon?
- A. Serotonin
- B. Leukotrienes
- C. Histamine
- D. Bradykinin
- E. Interleukin-I
Hint
Think of the cytokine released by activated macrophages that acts on the hypothalamic thermoregulatory centre through prostaglandin E₂ to raise the temperature set point.
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