KROK 1 2008 – Question 151 · KROK (Medicine) · Pathophysiology

Parents of a 3 year old child have been giving him antibiotics with purpose of preventing enteric infections for a long time. A month later the child’s condition changed for the worse. Blood examination revealed apparent leukopenia and granulocytopenia. What is the most probable mechanism of blood changes?

  1. A. Autoimmune
  2. B. Myelotoxic
  3. C. Hemolytic
  4. D. Redistributive
  5. E. Age-specific
Hint

Consider where granulocytes are produced and what long, unsupervised antibiotic use can do to the precursor cells in that organ.

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