KROK 1 2008 – Question 142 · KROK (Medicine) · Pathomorphology

A 38 year old patient with full-blown jaundice, small cutaneous hemorrhages, general weakness and loss of appetite underwent puncture biopsy of liver. Histological examination revealed disseminated dystrophy, hepatocyte necrosis, Councilman’s bodies. Lobule periphery has signs of significant infiltration by lymphocytes, there are also individual multinuclear hepatocytes. What is the most probable diagnosis?

  1. A. Toxic degeneration of liver
  2. B. Acute alcoholic hepatitis
  3. C. Miliary hepatic cirrhosis
  4. D. Chronic hepatitis
  5. E. Acute viral hepatitis
Hint

Think about the liver lesion in which apoptotic hepatocytes and a lymphocytic infiltrate appear together in a jaundiced patient with an acute infectious process.

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