KROK 1 2023 – Question 135 · KROK (Medicine) · Pathophysiology

Against the background of ionizing radiation exposure, a decrease in the granulocyte count was detected in the patient's blood. What causes agranulocytosis in this case?

  1. A. Autoimmune process development
  2. B. Disturbed release of mature leukocytes from the bone marrow
  3. C. Increased migration of granulocytes into tissues
  4. D. Leukopoiesis inhibition
  5. E. Increased leukocyte destruction
Hint

Consider where granulocytes are produced and how rapidly dividing precursor cells respond to ionizing radiation.

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