KROK 1 2023 – Question 76 · KROK (Medicine) · Pathophysiology

A 26-year-old woman, who one year ago had a difficult childbirth with a hemorrhage, complains of general weakness, weight loss of 18 kg, and absence of menstruations. Objectively, she has mammary hypoplasia. She was diagnosed with Simmonds disease. What is the main mechanism of the weight loss in this woman?

  1. A. Decreased production of adenohypophysis hormones
  2. B. Hypoparathyroidism
  3. C. Decreased function of the gonads
  4. D. Hypothyroidism
  5. E. Decreased function of the adrenal cortex
Hint

Think about what a pituitary infarction after massive postpartum bleeding switches off, and which single central failure sits upstream of several other endocrine deficits.

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