KROK 1 2018 – Question 93 · KROK (Medicine) · Pathophysiology
A 38-year-old man, who has been suffering from systemic lupus erythematosus for 3 years, developed diffuse renal lesions accompanied by massive edemas, marked proteinuria, hyperlipidemia, and dysproteinemia. What is the most likely mechanism of proteinuria development in this case?
- A. Inflammatory damage to the nephrons
- B. Morbid affection of the urinary tracts
- C. Ischemic damage to the tubules
- D. Increased blood proteins
- E. Autoimmune damage to the nephrons
Hint
Consider what the underlying disease does to the glomerular filtration barrier, and what kind of injury would allow massive loss of protein into the urine.
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