KROK 1 2018 – Question 2 · KROK (Medicine) · Pathomorphology

Autopsy of a woman revealed the following morphologic changes: stenosis of the atrioventricular opening, mitral insufficiency. Histologically there are focal cardiosclerosis and ”blooming” Aschoff nodules in the myocardium. What is the most likely diagnosis?

  1. A. Scleroderma
  2. B. Systemic lupus erythematosus
  3. C. Rheumatism
  4. D. Polyarteritis nodosa
  5. E. Dermatomyositis
Hint

Ask which systemic inflammatory disease of connective tissue produces both a characteristic myocardial granuloma and a chronic deformity of the mitral valve.

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