KROK 1 2017 – Question 146 · KROK (Medicine) · Pathophysiology

Examination of a 56-year-old woman with a history of type 1 diabetes revealed a disorder of protein metabolism that is manifested by aminoacidemia in the laboratory blood test values, and clinically by the delayed wound healing and decreased synthesis of antibodies. Which of the following mechanisms causes the development of aminoacidemia?

  1. A. Increase in plasma oncotic pressure
  2. B. Decrease in concentration of blood amino acids
  3. C. Increase in low-density lipoproteins level
  4. D. Increased proteolysis
  5. E. Albuminosis
Hint

Think about insulin's anabolic role in protein turnover and what happens to tissue proteins and the amino acid pool when that effect is lost.

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