KROK 1 2017 – Question 40 · KROK (Medicine) · Pathomorphology

On autopsy of a 40-year-old woman, who had been suffering from rheumatoid arthritis, her spleen is found to be dense and enlarged. On dissection its tissue is red-brown colored, with enlarged follicles resembling semi-transparent grayish-white granules. What is the most likely pathological process?

  1. A. Porphyry spleen
  2. B. Splenic hyalinosis
  3. C. Sago spleen
  4. D. Sugar-coated spleen
  5. E. Lardaceous spleen
Hint

Think about which complication of long-standing inflammatory disease affects the spleen, and which gross pattern places the abnormal material in the follicles versus the red pulp.

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