KROK 1 2016 – Question 36 · KROK (Medicine) · Pathomorphology

A man is 28 years old. Histological investigation of the cervical lymph node revealed a change of its pattern due to proliferation of epithelioid, lymphoid cells and macrophages with horseshoe-shaped nuclei. In the center of some cell clusters there were non-structured light-pink areas with fragments of nuclei. What disease are these changes typical of?

  1. A. Actinomycosis
  2. B. Syphilis
  3. C. Tumor metastasis
  4. D. Tuberculosis
  5. E. Hodgkin’s disease
Hint

Combine the cell composition of the clusters with the amorphous pink centre containing nuclear debris, and ask which type of necrosis and which kind of granuloma this describes.

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