KROK 1 2015 – Question 85 · KROK (Medicine) · Microbiology, Virology, and Immunology

Parents of a 5-year-old boy report him to have frequent colds that develop into pneumonias, presence of purulent rashes on the skin. Laboratory tests have revealed the following: absence of immunoglobulins of any type, and naked cells are absent from the lymph nodes punctate. What kind of immune disorder is it?

  1. A. Autosomal recessive agammaglobulinaemia (Swiss type)
  2. B. X-linked hypogammaglobulinemia (Bruton type agammaglobulinemia)
  3. C. Hypoplastic anemia
  4. D. Agranulocytosis
  5. E. Louis-Barr syndrome
Hint

Ask which arm of immunity fails when no antibody-secreting cells can be found, and why a boy gets recurrent pyogenic infections only after his first months of life.

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