KROK 1 2015 – Question 35 · KROK (Medicine) · Pathophysiology
A 12-year-old child has developed nephritic syndrome (proteinuria, hematuria, cylindruria) 2 weeks after the case of tonsillitis, which is a sign of affected glomerular basement membrane in the kidneys. What mechanism is the most likely to cause the basement membrane damage?
- A. Cytotoxic
- B. Reaginic
- C. Granulomatous
- D. Antibody-mediated
- E. Immune complex
Hint
Think about the typical delay between a streptococcal throat infection and the kidney injury, and which hypersensitivity mechanism explains damage arising at that time.
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