KROK 1 2014 – Question 157 · KROK (Medicine) · Pathomorphology

Autopsy has revealed shrunken kidneys weighing 50 g, with fine-grained surface and uniformly thinned substance. Microscopic investigation has shown the thickening of arteriole walls due to accumulation of homogeneous anhistic pink-coloured masses in them. Glomerules were undersized, sclerotic, with atrophied tubules. What disease are these changes characteristic of?

  1. A. Renal amyloidosis
  2. B. Essential hypertension
  3. C. Acute glomerulonephritis
  4. D. Pyelonephritis with kidney shrinkage
  5. E. Membranous nephropathy
Hint

Link the hyaline thickening of the arterioles to its effect on the nephrons and on kidney size, and consider whether the surface scarring is fine and symmetrical or coarse and uneven.

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