KROK 1 2014 – Question 141 · KROK (Medicine) · Microbiology, Virology, and Immunology

Hepatitis B is diagnosed through laboratory tests that determine the presence of HBV-DNA in blood serum of the patient. What reference method is applied for this purpose?

  1. A. ELISA diagnostic method
  2. B. Hybridization method
  3. C. Polymerase chain reaction
  4. D. Ligase chain reaction method
  5. E. Hybridization signal amplification method
Hint

Think about how the viral nucleic acid itself, present in tiny amounts in serum, is best detected and quantified, as opposed to the host's response to the virus.

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