KROK 1 2013 – Question 166 · KROK (Medicine) · Pharmacology

A patient with arthritis and varicose veins has been taking a non-steroidal antiinflammatory drug for a long time, which caused thrombosis of skin veins. Which of the following drugs might have caused this complication?

  1. A. Aspirin
  2. B. Ibuprofen
  3. C. Phenylbutazone
  4. D. Indomethacin
  5. E. Celecoxib
Hint

Think about how an anti-inflammatory drug could tip the balance between vessel-wall prostacyclin and platelet thromboxane towards clotting instead of away from it.

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