KROK 1 2013 – Question 104 · KROK (Medicine) · Pathophysiology

A 35-year-old male developed acute heart failure while running for a long time. What changes in the ionic composition can be observed in the cardiac muscle?

  1. A. Reduction of K+ and Mg2+ ions in the extracellular space
  2. B. Accumulation of Na+ and Ca2+ ions in the myocardium cells
  3. C. Reduction of Na+ and Ca2+ ions in the myocardium cells
  4. D. Accumulation of K+ and Mg2+ ions in the myocardium cells
  5. E. Reduction of Na+ and Ca2+ ions in the extracellular space
Hint

Consider what happens to the energy-dependent ion pumps of a cardiomyocyte during exhausting overload, and in which direction each ion then moves across the membrane.

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