KROK 1 2012 – Question 190 · KROK (Medicine) · Microbiology, Virology, and Immunology
A 45 year old male died from disseminated tuberculosis. On autopsy the symptoms of tuberculosis were confirmed by both microscopical and histological analyses. All the affected organs had epithelioid cell granulomas with caseous necrosis in the centre. What kind of hypersensitivity reaction underlies the process of granuloma development?
- A. Immune complex
- B. Complement-dependent cytotoxicity
- C. Anaphylactic
- D. Delayed
- E. Antibody-dependent cytotoxicity
Hint
Consider which immune cells and mediators are needed to build epithelioid granulomas around a persistent intracellular organism.
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