KROK 1 2011 – Question 177 · KROK (Medicine) · Pharmacology

A doctor prescribed a cephalosporin antibiotic to the patient after appendectomy for infection prevention. Antimicrobial activity of this group of antibiotics is based upon the disturbance of the following process:

  1. A. Energy metabolism
  2. B. Nucleic acid synthesis
  3. C. Choline esterase block
  4. D. Microbial wall formation
  5. E. Ribosome protein synthesis
Hint

Think about how cephalosporins, as beta-lactams, bind penicillin-binding proteins and why this kills growing bacteria while sparing human cells.

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