KROK 1 2011 – Question 10 · KROK (Medicine) · Pharmacology
A patient suffering from stomach ulcer has been treated with an antacid drug almagel. For acute bronchitis treatment he was prescribed the antibiotic methacycline. However within next 5 days the fever didn’t fall, cough and sputum nature remained unchanged. A physician came to the conclusion that the drugs were incompatible. What type of drug incompatibility is the case?
- A. Pharmaceutic
- B. Direct antagonism
- C. Pharmacodynamic
- D. Pharmacokinetic, biotransformation stage
- E. Pharmacokinetic, absorption stage
Hint
Think about where in the body the two drugs first meet, and what an antacid containing metal ions might do to a tetracycline at that site.
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