Question 103 · LEK · Wilson's disease

Which of the following are characteristic of Wilson disease in children?

1) excessive storage of copper in the liver accompanied by the increased serum activity of aminotransferases;
2) frequent neurological disorders, especially dysarthria;
3) frequent presence of Kayser-Fleischer ring of the cornea;
4) increased serum ceruloplasmin concentration;
5) increased urinary copper excretion.
The correct answer is:
  1. A. 1,2.
  2. B. 1,3.
  3. C. 1,5.
  4. D. 1,3,5.
  5. E. 1,3,4,5.
Hint

Consider which form of Wilson disease dominates in young children and in which direction ceruloplasmin and urinary copper change.

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