Question 89 · LEK · Cystic fibrosis
Cystic fibrosis consists in inherited malfunction of the chloride channel. It results in the decreased excretion of chloride and the increased absorption of natrium into cells, which leads to ion disturbances and dehydration of the secretion of exocrine glands. Thus, it is true that in children with cystic fibrosis more often than in healthy children:
1) sweat contains less chloride, which is used in the diagnostics;
2) bronchiectasis may occur;
3) cholestasis and cholelithiasis may occur;
4) sinusitis and nasal polyps may occur;
5) exocrine pancreatic insufficiency may be observed while the endocrine pancreatic function is preserved (e.g. insulin secretion).
The correct answer is:
2) bronchiectasis may occur;
3) cholestasis and cholelithiasis may occur;
4) sinusitis and nasal polyps may occur;
5) exocrine pancreatic insufficiency may be observed while the endocrine pancreatic function is preserved (e.g. insulin secretion).
The correct answer is:
- A. only 1.
- B. 2,3.
- C. 2,3,4.
- D. 2,3,4,5.
- E. 1,2,3,4.
Hint
Recall what the sweat test actually measures in CF and whether pancreatic endocrine function stays intact over time.
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