Question 84 · LEK · Leukemias
Acute lymphoblastic leukemia (ALL) in a child population presents a relatively good prognosis compared with other neoplastic diseases. Which of the following is a prognostic high risk factor in ALL in children that urges intensive treatment and decreases chances of curing the disease?
- A. susceptibility to introductory glucocorticoid treatment.
- B. presence of translocation t(9;22).
- C. normal leukocyte count at the diagnosis of the bone marrow infiltration by leukemic cells.
- D. coexisting Down syndrome.
- E. no trace of minimal residual disease in bone marrow after one-month treatment.
Hint
Sort the options into favorable and unfavorable prognostic features; only one is a classic high-risk criterion.
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