Question 64 · LEK · Severe combined immunodeficiency (SCID)

Indicate the true statements concerning the severe combined immunodeficiency (SCID):

1) it is a genetic disorder consisting in the absence or dysfunction of lymphocytes T that may be accompanied by the absence of lymphocytes B, NK or other cells of the hematologic system;
2) it is the most common type of primary immunodeficiency in children;
3) if left untreated it usually leads to death in the first year of life;
4) hematopoietic cell transplantation may result in permanent cure;
5) it may be radically treated by regular administration of immunoglobulins.
The correct answer is:
  1. A. 1,2,4.
  2. B. 1,3,4.
  3. C. 2,3,4.
  4. D. 2,3,5.
  5. E. 3,4,5.
Hint

Ask which primary immunodeficiencies are most frequent and whether immunoglobulin replacement can restore T-cell immunity.

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