Question 148 · LEK · Endometrial cancer

A 65-year-old patient in good medical condition, with arterial hypertension and type 2 diabetes mellitus treated with oral therapy, comes to the gynecologist because of the moderate hemorrhage from the reproductive tract. Her body weight is 87 kg and the height is 163 cm. The result of the endometrial biopsy is: endometrial adenocarcinoma G1. Transvaginal ultrasound imaging suggests minimal invasion of the endometrium, CT imaging shows no intra-abdominal dissemination nor pathological pelvic or paraaortic lymph nodes. Indicate the optimal treatment for this patient:

  1. A. surgery: hysteroscopic removal of the tumor.
  2. B. surgery: panhysterectomy.
  3. C. radiotherapy (brachytherapy + teletherapy).
  4. D. chemotherapy (paclitaxel + carboplatin).
  5. E. hormonal (megestrol acetate).
Hint

For an early-stage, low-grade endometrioid cancer in a medically fit woman, think of the standard definitive primary treatment.

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