Question 125 · LEK · Assessment of fetal condition and development
Indicate the true statements concerning the double test in prenatal diagnostics:
1) it is performed between 11th and 14th week of gestation;
2) it assesses 2 biochemical markers in the blood of the pregnant woman;
3) in the case of a fetus with Down syndrome the concentration of free beta hCG subunit is decreased;
4) in the case of a fetus with Down syndrome the concentration of PAPP-A is decreased;
5) in the case of a fetus with Edwards syndrome the concentration of free beta hCG subunit is decreased.
The correct answer is:
2) it assesses 2 biochemical markers in the blood of the pregnant woman;
3) in the case of a fetus with Down syndrome the concentration of free beta hCG subunit is decreased;
4) in the case of a fetus with Down syndrome the concentration of PAPP-A is decreased;
5) in the case of a fetus with Edwards syndrome the concentration of free beta hCG subunit is decreased.
The correct answer is:
- A. 1,2,3,4.
- B. 1,3,4,5.
- C. 2,3,4,5.
- D. 1,2,4,5.
- E. all the above.
Hint
Recall the marker pattern in trisomy 21 (one marker up, one down) compared with trisomy 18 (both down).
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