Question 58 (part 2) · LEK · Interstitial lung diseases

In spirometry, interstitial lung diseases e.g. idiopathic pulmonary fibrosis or sarcoidosis cause the following abnormalities in forced vital capacity (FVC) and forced expiratory volume in the first second (FEV1):

  1. A. a decreased FEV1/FVC ratio, which indicates restrictive defects.
  2. B. a decreased FEV1/FVC ratio, which indicates obstructive defects.
  3. C. a decreased FVC and a normal FEV1/FVC ratio, which indicates obstructive defects.
  4. D. a decreased FVC and a normal FEV1/FVC ratio, which indicates restrictive defects.
  5. E. a decreased FEV1and a normal FEV1/FVC ratio, which indicates obstructive defects.
Hint

Fibrosis shrinks lung volumes but does not narrow the airways – what happens to the FEV1/FVC ratio?

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