Question 46 (part 2) · LEK · Pheochromocytoma and paraganglioma
A patient with a hormonally active pheochromocytoma requires pharmacological treatment in preparation for a surgical procedure. The treatment involves:
- A. the administration of a β-adrenolytic drug for 6 weeks and the addition of an α-adrenolytic drug in the case of a poor hypotensive effect.
- B. the administration of only an α-adrenolytic drug for 6 weeks; β-adrenolytic drugs are always contraindicated.
- C. the administration of an α-adrenolytic drug and the addition of a β-adrenolytic drug in the case of severe tachycardia
- D. the administration of an α-adrenolytic drug and the addition of a loop diuretic in the case of a poor hypotensive effect.
- E. the administration of an α-adrenolytic drug and the addition of a thiazide diuretic in the case of a poor hypotensive effect.
Hint
Which receptor must be blocked first to avoid unopposed vasoconstriction, and when does the other drug class become useful?
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